Videos from the PharmaTechnica Exhibitors

Following you will find videos produced by the exhibitors at the PharmaTechnica 2022. Take a look at the videos to already get an idea about the exhibitors and the products and services they will present at this year's expo.

Smart Clean Room: Implementation of the SMARTCR in an aseptic processing facility

  • Introduction to SMARTCR and functionality
  • Commissioning & Qualification
  • Case Study

Ana Fernandez, Telstar

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Investigating Vaporized Hydrogen Peroxide (VHP) – A appropriate process to decontaminate pre-sterilized vials

While the market for ready-to-use (RTU) containers is growing at a rapid pace, drug manufacturers are still looking for the ideal process, to transfer RTU vials into the fill & finish area of an isolator line. In an industry-first series of experiments, machine manufacturer Syntegon and drug containment solutions provider Stevanato Group have joined forces to examine the effects of Vaporized Hydrogen Peroxide (VHP) on pre-sterilized glass vials and, more importantly, on their content to prove VHP as a technology for proper outer decontamination of RTU packaging material.

Markus Heinz, Syntegon
Michele Guasti, Stevanato Group

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Robotics & Disposable, Keep up with trends

  • Product Loss Minimization in Robotic Fill & Finish process
  • Disposable Filling System as a perfect Choice for Small Production Scale Batches Robotic Fill & Finish process

Zaim Gashi, Steriline

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Containment in Pharma OSD Production

  • Critical Interfaces
  • Pilot Equipment for highly active products
  • Production Equipment and CIP

Michael Maintok, Glatt

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Visions for Pharmaceutical Freeze Drying

  • Examples of pharmaceutical freeze-drying applications
  • New developments in sustainable cooling, online moisture control and other areas

Christopher Proud, GEA Lyophil

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

The causes of defective tablets & capsules in pharmaceutical production?

  • What is the variety of defects in tablet and capsule production?
  • What are the causes of such defects?
  • How does a typical AQL for visual inspection look like?
  • What are the benefits of automatic visual inspection?

Dr. Miha Možina, Sensum

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Multi-purpose inspection of liquid drugs – Challenging flexibility and technical development

Demand for Fill&Finish lines for liquid drugs in the pharmaceutical market has been tremendous during the past years. Engineers as well as manufacturers have been challenged to meet growing expectations of customers for technical accuracy and scheduling of related projects. Due to the current, additional demand for vaccines while the rest of the market is still growing, producers as well as service providers are facing a new task. Among the established solution of semi-automatic inspection machines this is increasingly satisfied with fully automated lines, where a major part of both machine types shall be suitable for diverse products and formats.

The presentation outlines advantages and disadvantages of both types of inspection solutions and presents current projects and practical implementation. Furthermore, the major focus is placed on challenges for all project participants to plan, manufacture and qualify multi-purpose applications for those AVIs.

Florian Spribille, pixon engineering AG

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Transfer of ATMP Cell&Gene manufacturing into closed processing and how to validate 6-log decontamination

In this case study we will give you insight on how to bring your ATMP Cell&Gene manufacturing process to a higher sterility assurance level and do your process re-design into closed processing technology first time right. To minimize changing operator influence on product quality and to enhance product purity, the industry chooses to go into closed processing using isolator technology with reproducible H2O2 decontamination. To achieve this step a careful process re-organisation must be performed and suitable processing equipment needs thorough evaluation, which ultimately allows to present a validated system to the authorities. Follow us and see how it is done.

Martin Glättli, SME aseptic processing solutions
Milind Rokade, SME decontamination process validation

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Optimised Cleaning Processes with Augmented Reality

This video shows how the loading process of a wash load carrier can be optimized with AR (augmented reality) glasses to minimize the risk of a loading error. One of the biggest risks in cleaning systems is not that something in the system is not working but that the operator is not arranging the wash items correctly. With the help of augmented reality, we can reduce this risk and help make cleaning processes even more reliable.

Jochen Schlag, Belimed Life Science

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Answering the latest Annex 1 Requirements for Dry Heat Sterilization using CFD-Simulations

With the latest revision of the Annex 1 to the GMP guidelines a clear trend towards increasingly higher requirements for the manufacturing equipment of sterile medicinal products can be observed. A good example for this are the sections 8.66 to 8.71 from the latest draft which talk about the requirements for correct dry heat sterilization. With the help of CFD simulations of sterilization/depyrogenation tunnels, critical process parameters for validation required by these new articles, such as temperature (minimum and maximum temperatures), heat (distribution/uniformity) and airflows (correlated with the heat distribution) can be reliably calculated and visualised. The presentation demonstrates how the different aspects mentioned in the articles talking about dry heat sterilization in the latest annex 1 draft can be calculated and visualized using CFD. Furthermore, it will discuss the insights that are gained from the results and how they could be useful to a pharmacist in the approval process of the equipment, in case the articles get taken over into the final annex 1 revision.

Michael Chudoba, Bausch + Ströbel

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

Automated Optical Inspection Solutions for Pharmaceutical Production

The Crimping Control station BKS-400 exemplifies Optonic’s  approach to provide compact, easy to integrate inspection systems. They can be used for integration into new production machines or for retrofitting existing ones. The inspection systems provide a unified view to the user by using the “VisionCockpit” application. VisionCockpit is more than just an HMI, it’s a universal communications interface, which safeguards user access via LDAP (domain server) integration, collects and stores audit trails and connects SCADA systems, SQL databases and the PCL with all the inspection systems in a production line. The presentation provides details of the automated optical inspection system.

René Purwin, Optonic

Do you have questions to the speaker? Please send us your question to info@concept-heidelberg.de.

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